Speaker A
I did a genetic test with 10X.
Gary Brecka reveals his 10X genetic methylation test results with Dr. Carrie Sarda, explaining gene variants and their health impacts.
Ask about this video. Answers come from its transcript only — with the timestamp, so you can check them.
Generated from the transcript and can be wrong — check the timestamp.
Key Takeaways
- Methylation is a critical biochemical process impacting multiple health aspects.
- Gene variants can reduce methylation efficiency but can be managed with targeted supplements.
- Genetic testing can reveal actionable insights for personalized health optimization.
- Severe methylation disruptions are linked to serious mental and physical health conditions.
- Functional medicine approaches can effectively address gene-related health challenges.
What the video covers
- Gary Brecka undergoes a 10X genetic methylation test to analyze five key methylation genes.
- Dr. Carrie Sarda explains the significance of methylation in converting nutrients into usable forms.
- Genetic variants are categorized by color: green (normal), yellow (one variant), red (two variants).
- Gary’s results show mostly green and one yellow variant, indicating good gene function with minor inefficiency.
- Methylation affects sleep, thyroid, gut health, mood, detoxification, inflammation, and free radical defense.
- Supplementing with activated nutrients like methylated B12 can compensate for gene variants.
- Severe methylation gene disruptions correlate with mental illnesses, addiction, sleep disorders, and gut issues.
- Functional medicine and targeted supplementation can significantly improve or remediate symptoms.
- The test provides actionable genetic data rather than non-actionable physical traits.
- Understanding gene variants allows personalized health interventions to optimize overall wellbeing.
Full Transcript — Download SRT & Markdown
Speaker B
You did?
Speaker A
I did. And um, like you said, you're not able to give me the results of my test.
Speaker A
But I wanted to invite in Dr. Carrie Sarda, who's going to give me those results now. And she's going to explain a little bit to me about my results and also what the test is and what it means for me. So, I'm very excited to see the results.
Speaker B
I'm excited for you to see them.
Speaker B
Let's get her in.
Speaker A
A couple of days ago, I had someone come to my studio and they did a swab inside of my mouth for something called the 10X genetic methylation test, I believe.
Speaker A
What was that test?
Speaker A
And why did I do it?
Speaker B
You did it to look at the
Speaker B
five major genes of methylation.
Speaker B
So remember that if we pulled your entire genetic code, we would get a lot of non-actionable information. I could see that you have dark olive skin, you have dark eyes, you have detached your earlobes, but there's nothing you can do with that genetic information.
Speaker B
We want genetic information that's actionable.
Speaker B
So while you can't go in and fix the gene,
Speaker B
you can very often supplement for its function.
Speaker B
And the genes of methylation are very special because they code for the process of converting one raw material
Speaker B
into the usable form.
Speaker B
So in other words, we take in folic acid or its derivatives, but we convert it into a usable form called methylfolate.
Speaker B
And so this process is called methylation.
Speaker B
It's one of the most important process that human beings go through.
Speaker B
We do it 300 billion times a day.
Speaker B
And when you have breaks in certain genes,
Speaker B
this means that your body is not converting one raw material into the usable form.
Speaker B
And this causes a deficiency.
Speaker B
And very often it's this deficiency that leads to some of the most common ailments that we suffer from.
Speaker A
Dr. Carrie Sarda.
Speaker C
Hello.
Speaker C
Thanks for having me.
Speaker A
Could you give us a little bit of your bio and your background?
Speaker C
Sure. I my original training was surgical.
Speaker C
It was obstetrical and gynecology.
Speaker C
And I just found that um, more chronic disease was happening.
Speaker C
And people weren't really getting better.
Speaker C
And so my specialized training has been in functional medicine, kind of a more holistic approach.
Speaker C
I have two master's degrees in this.
Speaker C
And met up with um,
Speaker C
Mr. Breca.
Speaker B
Eight years ago.
Speaker B
Now.
Speaker B
It's been a while.
Speaker C
It's been a while.
Speaker C
And in a small room and and we started up um,
Speaker C
looking at these genetic tests and reasons that people were not getting better.
Speaker A
So I've got my test results here, which full disclosure, I'm yet to see.
Speaker C
So Jack over here is
Speaker A
So Jack over here is
Speaker C
put them on my iPad.
Speaker A
put them on my iPad.
Speaker C
And told me that I can swipe up and look at them.
Speaker A
And told me that I can swipe up and look at them.
Speaker A
So what am I looking at here?
Speaker A
And what does it tell me?
Speaker C
Okay, so with your permission
Speaker C
that we can share that, of course.
Speaker A
Only if it's good.
Speaker A
I'm joking.
Speaker C
That's important.
Speaker C
Well, I do.
Speaker C
I do want to tell you, your your parents did you a solid.
Speaker B
Yeah, they did.
Speaker B
You won the genetic lottery.
Speaker C
So remember that in genetics,
Speaker C
I think people get confused.
Speaker C
Genes are like blueprints.
Speaker C
So your mother writes half of that blueprint.
Speaker C
And your father writes the other half.
Speaker C
And you're born with that.
Speaker C
You'll take that to your grave.
Speaker C
So when you do have something that isn't quite exactly what you want it to be,
Speaker C
variant is the term that we tend to use.
Speaker C
When that does happen, we want to find out ways to work around that.
Speaker C
How we color code this to make it understandable is if you have a kind of a normal copy and a normal copy from each parent,
Speaker C
that's green.
Speaker C
And if you have one copy from a parent that is normal, but one copy that is not,
Speaker C
we're going to color that yellow.
Speaker C
And you have one of those.
Speaker C
And if you have both copies are not normal, that's red.
Speaker C
And you don't have any of those,
Speaker C
which is great.
Speaker C
And the significance to that is the green genes will code 100%.
Speaker C
You're good to go.
Speaker C
Yellow genes about 40%.
Speaker C
Red genes 10 or less.
Speaker C
And so kind of think of it like putting spokes in a wheel.
Speaker C
It just kind of clogging it up.
Speaker C
Because these genes do follow a pathway.
Speaker C
It's the methylation pathway.
Speaker C
I like to think of methylation as activation.
Speaker C
Like we talked about taking something raw, bring it in and allowing your cells to convert it to what it can use.
Speaker C
So if you have any glitches in the pathway, you're not going to be as efficient.
Speaker C
So you would want to correct for your one variant gene there.
Speaker C
So you come in nicely with that first gene, that's probably the most common one and that's the real popular one.
Speaker C
Um, we kind of take it next level.
Speaker C
We follow the pathway all the way up.
Speaker C
And the reason why this even matters is because it affects everything on you.
Speaker C
It affects how you sleep.
Speaker C
It affects ultimately,
Speaker C
down the road.
Speaker C
At a deeper level.
Speaker C
How you sleep.
Speaker C
How your thyroid functions, how your gut functions.
Speaker C
How your moods.
Speaker C
How you detox, especially heavy metals.
Speaker C
How you detox.
Speaker C
It affects your inflammation in your body.
Speaker C
How well you can fight free radicals.
Speaker C
Those are all important things.
Speaker C
And that's why this is more than just data.
Speaker C
Um, it's real data.
Speaker C
So for if you do not correct your one yellow,
Speaker C
you're not going to be as good at doing all those things.
Speaker C
Detoxing, fighting inflammation.
Speaker C
Your gut movement.
Speaker C
Those kinds of things.
Speaker C
And it's a pretty simple fix for you.
Speaker C
If you don't activate activate those nutrients,
Speaker C
then let's give you activated nutrients.
Speaker C
For example,
Speaker C
you most likely have trouble activating B12.
Speaker C
That's probably an issue that that you're not as efficient at.
Speaker C
Of course you do it.
Speaker C
But you're not as efficient at it.
Speaker C
Because it wasn't green.
Speaker C
So we you would want to therefore take the activated B12 form, the methylated B12 form.
Speaker C
So by doing that every day, I kind of liken it to the road is broken, but you've built a bridge over it.
Speaker C
So that's how you can um, compensate for that.
Speaker C
Gene variant or that gene break.
Speaker C
We like to kind of lovingly call them.
Speaker A
On my results, it says one parent passed on a gene mutation.
Speaker A
Which one was it?
Speaker C
So that's right.
Speaker C
So so that's that's
Speaker B
You want to know who to blame.
Speaker C
So that's the thing.
Speaker C
Unless you tested your parents, you're not going to really know who gave you what.
Speaker A
Okay.
Speaker C
You do know that you had one that gave you a normal gene and one that gave you a variant.
Speaker C
And that's why it's yellow.
Speaker A
What else does this mean for me on a practical level?
Speaker A
Does this mean that I'm going to like, you know, I want to know if there's any sort of health implications that I should be aware of?
Speaker C
So anytime you have any kind of variant in your methylation, especially in the lower pathway,
Speaker C
you have to understand that it is going to affect it all the way up.
Speaker C
So when so effects can be all the way from simple sleep issues to all the way to not being able to sleep at all.
Speaker C
Uh, can be mood, uh, gut issues.
Speaker A
Okay.
Speaker B
But you can take it out of the loop with the supplement.
Speaker A
Are you able to tell me about the worst sort of profile you've seen?
Speaker A
And the sort of real world consequences of that when all five markers of their
Speaker B
are are interrupted.
Speaker B
Yeah, we've seen them where
Speaker B
there's a heavy mix of red and green.
Speaker A
Okay.
Speaker B
Um, and this is where you see significant um, personality alterations, significant um,
Speaker B
what we would refer to as mental illness, severe ADD, ADHD, OCD,
Speaker B
manic depression, bipolar.
Speaker B
Um, you see very high propensities for addiction because of the depleted level of dopamine.
Speaker B
Um, you see significant sleep disorders, um, very severe gut issues, gas, bloating, diarrhea, constipation, irritability, cramping that don't seem to be fixable with conventional therapies or dietary changes.
Speaker B
Um, those are amazing cases to watch the clinical team work with because
Speaker B
by getting methylation right, I have seen those cases solved by our clinical team.
Speaker B
And and and many of those symptoms become fully remissive.
Speaker B
And we get a lot of chances to make good people great.
Speaker B
But when you can materially change somebody's life, um,
Speaker B
by fixing those gene mutations,
Speaker B
that's when you're really making an impact.
Speaker A
These five acronyms here, COMT, and then it says mind.
Speaker A
AHCY, then it says mind.
Speaker A
MTRR, then it says upper gut.
Speaker A
MTR, that says lower gut.
Speaker A
That's the one that I have this yellow one on.
Speaker A
And then there's the motherfucker one, I shouldn't say that, the MTHFR, which is mind and gut.
Speaker A
These are the five sort of factors for methylation,
Speaker A
which is really about how I process the ingredients I put in my body.
Speaker B
Yes.
Speaker A
And I'm guessing that these are at different stages in my body.
Speaker A
So the ones that say mind are in my head.
Speaker A
The one that says upper gut is sort of higher up in my gut.
Speaker A
The one that says lower up is in my lower gut.
Speaker A
And then this MTHFR that says mind and gut, that's that's
Speaker B
Yes.
Speaker B
And the reason is that
Speaker B
remember these are sequential.
Speaker A
Okay.
Speaker B
Right?
Speaker B
So
Speaker B
I always use the analogy that think of it like a sandbag pass, right?
Speaker B
So you have a bunch of guys lined up and you have one guy that's taking the sandbags off the truck.
Speaker B
And passing it to the next guy.
Speaker B
And he passes it to the next guy and so on.
Speaker B
Well, if if early in that chain, he was supposed to take 10 sandbags off the truck.
Speaker B
But he dropped four.
Speaker B
The best the rest of the line could do is six.
Speaker B
So in other words, if an early gene like MTHFR, which is early in the methylation cycle is impaired,
Speaker B
it impairs the entire downstream.
Speaker B
And if several gene snips later, you have another major gene snip, it will impair things further downstream.
Speaker A
Ah, so is that what you tend to see if someone has the
Speaker B
Yes.
Speaker B
This is why if you Google consequences of MTHFR or MTHFR and um, miscarriages, MTHFR and ADD, MTHFR and ADHD, MTHFR and anxiety.
Speaker B
You're going to see hordes of articles and and clinical studies
Speaker B
linking that gene mutation to what seems like a vast myriad of consequences.
Speaker B
Well, that vast myriad of consequences is actually related to the gene snips that are further downstream.
Speaker B
But they're affected because they're not getting the raw material they need to do their job.
Speaker B
And and in my opinion, it's one of the most overlooked things in all of modern medicine.
Speaker B
As simple as this test is and is easily and widely available as it is.
Speaker B
I'm surprised that more frontline clinics do not do this.
Speaker B
Because people do it once in their lifetime.
Speaker B
And they supplement for deficiency.
Speaker B
And sometimes you see miraculous changes in their life.
Speaker A
Gary, thank you.
Speaker A
I'm going to put this these results, my results in the description of this episode below, exactly as it is here in front of me.
Speaker A
So everyone can see and the details of how I got the test done, etc.
Speaker A
will all be available there for you guys to to check out.
Speaker A
If you love the Diary of a CEO brand and you watch this channel, please do me a huge favor.
Speaker A
Become part of the 15% of the viewers on this channel that have hit the subscribe button.
Speaker A
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Topics:Gary BreckaSteven Bartlett10X genetic testmethylationgene variantsfunctional medicinegenetic testinghealth optimizationmethylated B12chronic disease
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